Evolutionary engineering, also known as adaptive laboratory evolution (ALE), is commonly used in biological research to acquire new and desirable traits in microbes and enzymes. The desired traits include improving microbial tolerance to unfavorable environmental conditions, better and efficient use of various substrates, improvement of product yield, and even better enzymes, all of which are critically important for development of efficient microbial cell factories. Although the rational-design-based synthetic biology and metabolic engineering are mutually complementary to each other, the evolutionary engineering is convenient to use as a useful tool to overcome the overwhelmingly complexity of biological systems and fast development of industrial strains. Equipment for ALE has undergone a continuous enhancement for a more controllable experimental design and longer operation. Further, integration of automated evolutionary engineering to metabolic engineering and synthetic biology emerged as promising synthetic-evolution strategy.
There are plenty of DIY chemostat, ministat, turbidostat, available online, with great and easy designs
As I learned much from those amazing previous studies, I tried to develop something:
Simple design, easy operation, with broad applications
What can customized Bioreactor do for your experiment?
Adaptive evolution strategies